By Samuel Reaves Slaton

The real world's got nothing on the invented substances found in the trippiest works of literature, like A Clockwork Orange, The Lord of the Rings and Infinite Jest. MORE  

By Chloe Caldwell

I always prided myself on my ability to handle my drugs. Now that I’m making my first clutches at sobriety, I’m beginning to see that I’d much rather be able to handle me. MORE  

By Amy Dresner

In my early twenties, I discovered speed. The affair was short but not at all sweet—unless you count the all Caramello bars. MORE  

By Tony O'Neill

More teenagers are using heroin than ever before, thanks in part to the opiate introduction they’re getting prescribed. Just another way the War on Drugs is missing the mark. MORE  

By Cole Louison

Exactly 18 years after the suicide of Kurt Cobain, The Fix unveils five of his original artworks. A dark look into the mind of a tortured heroin addict, they're also ground zero in a battle between Cobain's widow and his publishing company. MORE  

By Tony O'Neill

The writer's newly-released letters prove that his wasted image was much more than a pose. MORE  

By Jeff Deeney

William S. Burroughs gives a new spin to the season with some help from Francis Ford Coppola.  MORE  

By Nicolas Rasmussen

Back in the sixties, a slew of star writers like Allen Ginsberg, Jack Kerouac, and William Burroughs radically increased their output by consuming vast amounts of of speed. But eventually the drug did them more harm than good. MORE  

By Tony O'Neill

Russia’s newest bathtub morphine is a nightmare straight from Naked Lunch. MORE  

By Tony O'Neill

AA's total-abstinence policy works for many addicts. But it didn't work for me. After a decade of heroin hell it took a newborn baby and a few tabs of ecstasy to finally set me free. MORE